Publications des enseignants de biologie cellulaire – Département de biologie cellulaire

2017

Kilens S, Meistermann D, Moreno D, Chariau C, Gaignerie A, Reignier A, Lelièvre Y, Casanova M, Vallot C, Nedellec S, Flippe L, Firmin J, Song J, Charpentier E, Lammers J, Donnart A, Marec N, Deb W, Bihouée A, Consortium The Milieu Intérieur, Le Caignec C, Pecqueur C, Redon R, Barrière P, Bourdon J, Pasque V, Soumillon M, Mikkelsen T S, Rougeulle C, Fréour T, David L. Parallel derivation of isogenic human primed and naïve induced pluripotent stem cells. Nature Communications 2017 (sous presse).
Dirou S, Chambellan A, Chevallier P, Germaud P, Lamirault G, Gourraud PA, Perrot B, Delasalle B, Forestier B, Guillaume T, Peterlin P, Garnier A, Magnan A, Blanc FX, Lemarchand P. Deconditioning, fatigue and impaired quality of life in long-term survivors after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplantation 2017 (sous presse).
Lamirault G, de Bock E, Sébille S, Delasalle B, Roncalli J, Susen S, Piot C, Trochu JN, Teiger E, Neuder Y, Le Tourneau T, Manrique A, Hardouin J-B, Lemarchand P. Sustained quality of life improvement after intracoronary injection of autologous bone marrow cells in the setting of acute myocardial infarction: results from the BONAMI trial. Quality of Life Research 2017; 26:121–125.
Nicol B, Salou M, Vogel I, Garcia A, Dugast E, Morille J, Kilens S, Charpentier E, Donnart A, Nedellec S, Jacq-Foucher M, Le Frère F, Wiertlewski S, Bourreille A, Brouard S, Michel L, David L, Gourraud PA, Degauque N, Nicot AB, Berthelot L, Laplaud DA. An intermediate level of CD161 expression defines a novel activated, inflammatory, and pathogenic subset of CD8(+) T cells involved in multiple sclerosis. J Autoimmun. 2017 Oct 17.
Chambellan A, Nusinovici S, Vaidya T, Gourraud PA, de Bisschop C. The validation of the sit-to-stand test for COPD patients. Eur Respir J. 2017 20;50(3).
Le Berre L, Rousse J, Gourraud PA, Imbert-Marcille BM, Salama A, Evanno G, Semana G, Nicot A, Dugast E, Guérif P, Adjaoud C, Freour T, Brouard S, Agbalika F, Marignier R, Brassat D, Laplaud DA, Drouet E, Van Pesch V, Soulillou JP. Decrease of blood anti-α1,3 Galactose Abs levels in multiple sclerosis (MS) and clinically isolated syndrome (CIS) patients. Clin Immunol. 2017 ;180:128-135.
Pappas DJ, Lizee A, Paunic V, Beutner KR, Motyer A, Vukcevic D, Leslie S, Biesiada J, Meller J, Taylor KD, Zheng X, Zhao LP, Gourraud PA, Hollenbach JA, Mack SJ, Maiers M. Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest. Pharmacogenomics J. 2017 Apr 25.
Johnston HR, Hu YJ, Gao J, O’Connor TD, Abecasis GR, Wojcik GL, Gignoux CR, Gourraud PA, Lizee A, Hansen M, Genuario R, Bullis D, Lawley C, Kenny EE, Bustamante C, Beaty TH, Mathias RA, Barnes KC, Qin ZS; CAAPA Consortium. Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome. Sci Rep. 2017 ;7:46398.
Findlay GM, David L, Beyer TA. Molecular Mechanisms of Stem Cell Pluripotency and Cell Fate Specification. J Mol Biol. 2017 ;429(10):1439-1440.
Picarda E, Bézie S, Boucault L, Autrusseau E, Kilens S, Meistermann D, Martinet B, Daguin V, Donnart A, Charpentier E, David L, Anegon I, Guillonneau C. Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells. JCI Insight. 2017 ;2(3):e90088.
Guillonneau C, David L, Anegon I. Improved Analyses of CD8+ T Cell Specificities Using Multimers of Peptide MHC Complexes Coupled to DNA Barcodes. Transplantation. 2017;101(2):219-221.

2016

Le Bourgeois A, Malard F, Chevallier P, Urbistandoy U, Guillaume Th, Delaunay J, Peterlin P, Lemarchand P, Germaud P, Mohty M, Moreau Ph, Chambellan A. Impact of pre-transplant diffusion lung capacity for nitric oxide (DLNO) and of DLNO/pre-transplant diffusion lung capacity for carbon monoxide (DLNO/DLCO) ratio on pulmonary outcomes in adults receiving allogeneic stem cell transplantation for haematological diseases. Bone Marrow Transplantation 2016;51(4):589-92.
Si-Tayeb K, Idriss S, Champon B, Caillaud A, Pichelin M, Arnaud L, Lemarchand P, Le May C, Zibara K, Cariou B. Urine sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia. Disease Models & Mechanisms 2016; 9(1):81-90.
Manrique A, Lemarchand P, Delasalle B, Lairez O, Sportouch-Duckan C, Lamirault G, Le Corvoisier P, Neuder Y, Richardson M, Lebon A, Roncalli J, Piot C, Trochu JN, Teiger E, Hossein-Foucher C, Le Tourneau T. Predictors of ventricular remodelling in patients with reperfused acute myocardial infarction and left ventricular dysfunction candidates for bone marrow cell therapy: insights from the BONAMI trial. European Journal of Nuclear Medicine and Molecular Imaging 2016; 43(4):740–748.
Braza F, Dirou S, Forest V, Sauzeau V, Hassoun D, Chesné J, Cheminant-Muller M-A, Sagan C, Magnan A, Lemarchand P. Mesenchymal stem cells induce suppressive macrophages through phagocytosis in a mouse model of asthma. Stem Cells 2016 34(7):1836-45.
Guijarro D, Lebrin M, Lairez O, Bourin P, Piriou N, Pozzo J, Lande G, Berry M, Letourneau T, Cussac D, Sensebe L, Gross F, Lamirault G, Huynh A, Manrique A, Ruidavet JB, Elbaz M, Trochu JN, Parini A, Kramer S, Galinier M, Lemarchand P, Roncalli J. Intramyocardial transplantation of mesenchymal stromal cells for chronic myocardial ischemia and impaired left ventricular function: Results of the MESAMI 1 pilot trial. International Journal of Cardiology 2016; 209:258-265.
Lamirault G, de Bock E, Sébille S, Delasalle B, Roncalli J, Susen S, Piot C, Trochu JN, Teiger E, Neuder Y, Le Tourneau T, Manrique A, Hardouin J-B, Lemarchand P. Sustained quality of life improvement after intracoronary injection of autologous bone marrow cells in the setting of acute myocardial infarction: results from the BONAMI trial. Quality of Life Research 2016 Jul 20. [Epub ahead of print]
Es-Salah-Lamoureux Z, Jouni M, Malak OA, Belbachir N, Reda Al Sayed Z, Gandon-Renard M, Lamirault G, Gauthier C, Baró I, Charpentier F, Zibara K, Lemarchand P, Beaumelle B, Gaborit N, Loussouarn G. HIV-Tat induces a decrease in IKr and IKs via reduction in phosphatidylinositol-(4,5)-bisphosphate availability. Journal of Molecular and Cellular Cardiology (sous presse).
Lambert G, Chatelais M, Petrides F, Passard M, Thedrez A, Rye KA, Schwahn U, Gusarova V, Blom DJ, Sasiela W, Marais AD. Normalization of low-density lipoprotein receptor expression in receptor defective homozygous familial hypercholesterolemia by inhibition of PCSK9 with alirocumab. J Am Coll Cardiol. 2014 Dec 2;64(21):2299-300.

2015

Gyongyosi M, Wojakowski W, Lemarchand P, Lunde K, Tendera M, Bartunek J, Marbán E, Assmus B, Henry TD, Traverse JH, Moyé L, Suerder D, Corti R, Huikuri HV, Miettinen JA, Woehrle J, Obradovic S, Roncalli J, Malliaras K, Pokushalov E, Romanov A, Kastrup J, Bergmann MW, Atsma D, Cosmus Pyndt Diederichsen A, Édes I, Benedek I, Benedek T, Pejkov H, Nyolczas N, Pavo N, Bergler-Klein J, Pavo IJ, Sylven C, Berti S, Pio Navarese E, Maurer GM. Meta-Analysis of Cell-based CaRdiac stUdiEs (ACCRUE) in patients with acute myocardial infarction based on individual patient data. Circulation Research 2015 16(8):1346-60.
Jouni M, Si-Tayeb K, Es-Salah-Lamoureux Z, Latypova X, Champon B, Caillaud A, Rungoat A, Charpentier F, Loussouarn G, Baró I, Zibara K, Lemarchand P, Gaborit N. Towards Personalized Medicine: Using cardiomyocytes differentiated from urine-derived pluripotent stem cells to recapitulate electrophysiological characteristics of LQT2 syndrome. Journal of the American Heart Association 2015;4:e002159.
Croyal M, Ouguerram K, Passard M, Ferchaud-Roucher V, Chétiveaux M, Billon-Crossouard S, de Gouville AC, Lambert G, Krempf M, Nobécourt E. Effects of Extended-Release Nicotinic Acid on Apolipoprotein (a) Kinetics in Hypertriglyceridemic Patients. Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):2042-7.
Besseling J, Ong KL, Huijgen R, Rye KA, Hovingh GK, Hutten BA, Lambert G. The impact of LDLR function on fibroblast growth factor 21 levels. Atherosclerosis.2015 Aug;241(2):322-5.
Gencer B, Lambert G, Mach F. PCSK9 inhibitors. Swiss Med Wkly. 2015 Apr9;145:w14094.
Marais AD, Kim JB, Wasserman SM, Lambert G. PCSK9 inhibition in LDL cholesterol reduction: genetics and therapeutic implications of very low plasma lipoprotein levels. Pharmacol Ther. 2015 Jan;145:58-66.
Hopkins PN, Defesche J, Fouchier SW, Bruckert E, Luc G, Cariou B, Sjouke B, Leren TP, Harada-Shiba M, Mabuchi H, Rabès JP, Carrié A, van Heyningen C, Carreau V, Farnier M, Teoh YP, Bourbon M, Kawashiri MA, Nohara A, Soran H, Marais AD, Tada H, Abifadel M, Boileau C, Chanu B, Katsuda S, Kishimoto I, Lambert G, Makino H, Miyamoto Y, Pichelin M, Yagi K, Yamagishi M, Zair Y, Mellis S, Yancopoulos GD, Stahl N, Mendoza J, Du Y, Hamon S, Krempf M, Swergold GD. Characterization of Autosomal Dominant Hypercholesterolemia Caused by PCSK9 Gain of Function Mutations and Its Specific Treatment With Alirocumab, a PCSK9 Monoclonal Antibody. Circ Cardiovasc Genet. 2015 Dec;8(6):823-31.
Alves AC, Etxebarria A, Medeiros AM, Benito-Vicente A, Thedrez A, Passard M, Croyal M, Martin C, Lambert G, Bourbon M. Characterization of the first PCSK9 gain of function homozygote. J Am Coll Cardiol. 2015 Nov 10;66(19):2152-4.

2014

Delewi R, Hirsch A, Tijssen JG, Schächinger V, Wojakowski W, Roncalli J, Aakhus S, Erbs S, Assmus B, Tendera M, Goekmen Turan R, Corti R, Henry T, Lemarchand P, Lunde K, Cao F, Huikuri HV, Sürder D, Simari RD, Janssens S, Wollert KC, Plewka M, Grajek S, Traverse JH, Zijlstra F, Piek JJ. Impact of intracoronary bone marrow cell therapy on left ventricular function in the setting of ST-segment elevation myocardial infarction: a collaborative meta-analysis. Eur Heart J. 2014 Apr;35(15):989-98.
Dirou S, Malard F, Chambellan A, Chevallier P, Germaud P, Guillaume Th, Delaunay J, Moreau Ph, Delasalle B, Lemarchand P, Mohty M. Stable Long-Term Pulmonary Function after Fludarabine, antithymocyte globulin, and intravenous Busulfan for reduced-intensity conditioning allogeneic stem cell transplantation. Bone Marrow Transplantation 2014; 49(5):622-7
Tran-Dinh A, Levoye A, Lambert G, Louedec L, Journé C, Meilhac O, Amarenco P. Low levels of low-density lipoprotein-C associated with proprotein convertase subtilisin kexin 9 inhibition do not increase the risk of hemorrhagic transformation. Stroke. 2014 Oct;45(10):3086-8.
Kwakernaak AJ, Lambert G, Dullaart RP. Plasma proprotein convertase subtilisin-kexin type 9 is predominantly related to intermediate density lipoproteins. Clin Biochem. 2014 May;47(7-8):679-82.
Lambert G, Petrides F, Chatelais M, Blom DJ, Choque B, Tabet F, Wong G, Rye KA, Hooper AJ, Burnett JR, Barter PJ, Marais AD. Elevated plasma PCSK9 level is equally detrimental for patients with nonfamilial hypercholesterolemia and heterozygous familial hypercholesterolemia, irrespective of low-density lipoprotein receptor defects. J Am Coll Cardiol. 2014 Jun 10;63(22):2365-73.
Tabet F, Vickers KC, Cuesta Torres LF, Wiese CB, Shoucri BM, Lambert G, Catherinet C, Prado-Lourenco L, Levin MG, Thacker S, Sethupathy P, Barter PJ, Remaley AT, Rye KA. HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells. Nat Commun. 2014 Feb 28;5:3292
Marais AD, Kim JB, Wasserman SM, Lambert G. PCSK9 inhibition in LDL cholesterol reduction: genetics and therapeutic implications of very low plasma lipoprotein levels. Pharmacol Ther. 2015 Jan;145:58-66.
Gonzalez DR, Treuer AV, Lamirault G, Mayo V, Cao Y, Dulce RA, Hare JM. NADPH oxidase-2 inhibition restores contractility and intracellular calcium handling and reduces arrhythmogenicity in dystrophic cardiomyopathy. Am J Physiol Heart Circ Physiol. 2014 Sep 1;307(5):H710-21.

2013

Petrides F, Shearston K, Chatelais M, Guilbaud F, Meilhac O, Lambert G. The promises of pcsk9 inhibition. Curr Opin Lipidol. 2013;24:307-312
Kwakernaak AJ, Lambert G, Slagman MC, Waanders F, Laverman GD, Petrides F, Dikkeschei BD, Navis G, Dullaart RP. Proprotein convertase subtilisin-kexin type 9 is elevated in proteinuric subjects: Relationship with lipoprotein response to antiproteinuric treatment. Atherosclerosis. 2013;226:459-465
Kwakernaak AJ, Lambert G, Muller Kobold AC, Dullaart RP. Adiposity blunts the positive relationship of thyrotropin with proprotein convertase subtilisin-kexin type 9 levels in euthyroid subjects. Thyroid. 2013;23:166-172
Han H, Irimia M, Ross PJ, Sung HK, Alipanahi B, David L, Golipour A, Gabut M, Michael IP, Nachman EN, Wang E, Trcka D, Thompson T, O’Hanlon D, Slobodeniuc V, Barbosa-Morais NL, Burge CB, Moffat J, Frey BJ, Nagy A, Ellis J, Wrana JL, Blencowe BJ. Mbnl proteins repress es-cell-specific alternative splicing and reprogramming. Nature. 2013;498:241-245
Farokhi F, Grellier P, Clement M, Roussakis C, Loiseau PM, Genin-Seward E, Kornprobst JM, Barnathan G, Wielgosz-Collin G. Antimalarial activity of axidjiferosides, new beta-galactosylceramides from the african sponge axinyssa djiferi. Mar Drugs. 2013;11:1304-1315
David L, De Vos J. [reprogramming equals gambling?]. Med Sci (Paris). 2013;29:405-410
D.J. Blom, A.D. Marais, F.J. Raal, and G. Lambert (2013) “The potential use of monoclonal antibodies and other novel agents as drugs to lower LDL cholesterol ” Clin. Lipidol. 8,243-256.

2012

Beyer TA, Narimatsu M, Weiss A, David L, Wrana JL. The tgfbeta superfamily in stem cell biology and early mammalian embryonic development. Biochim Biophys Acta. 2013;1830:2268-2279
Pant Pai N, Balram B, Shivkumar S, Martinez-Cajas JL, Claessens C, Lambert G, Peeling RW, Joseph L. Head-to-head comparison of accuracy of a rapid point-of-care hiv test with oral versus whole-blood specimens: A systematic review and meta-analysis. Lancet Infect Dis. 2012;12:373-380
Oskouei BN, Lamirault G, Joseph C, Treuer AV, Landa S, Da Silva J, Hatzistergos K, Dauer M, Balkan W, McNiece I, Hare JM. Increased potency of cardiac stem cells compared with bone marrow mesenchymal stem cells in cardiac repair. Stem Cells Transl Med. 2012;1:116-124
Ogunjimi AA, Zeqiraj E, Ceccarelli DF, Sicheri F, Wrana JL, David L. Structural basis for specificity of tgfbeta family receptor small molecule inhibitors. Cell Signal. 2012;24:476-483
Mathieu E, Lamirault G, Toquet C, Lhommet P, Rederstorff E, Sourice S, Biteau K, Hulin P, Forest V, Weiss P, Guicheux J, Lemarchand P. Intramyocardial delivery of mesenchymal stem cell-seeded hydrogel preserves cardiac function and attenuates ventricular remodeling after myocardial infarction. PLoS One. 2012;7:e51991
Marais DA, Blom DJ, Petrides F, Goueffic Y, Lambert G. Proprotein convertase subtilisin/kexin type 9 inhibition. Curr Opin Lipidol. 2012;23:511-517
Malleter M, Jacquot C, Rousseau B, Tomasoni C, Juge M, Pineau A, Sakanian V, Roussakis C. Mirnas, a potential target in the treatment of non-small-cell lung carcinomas. Gene. 2012;506:355-359
Malleter M, Jacquot C, Rousseau B, Tomasoni C, Ducourneau D, Tourette P, Pineau A, Roussakis C. Study of antiproliferative effects of synthetic substances against lens epithelial cell line (sra 01/04). J Ocul Pharmacol Ther. 2012;28:299-306
Lambert G, Sjouke B, Choque B, Kastelein JJ, Hovingh GK. The pcsk9 decade. J Lipid Res. 2012;53:2515-2524
Kwakernaak AJ, Lambert G, Dullaart RP. Relationship of proprotein convertase subtilisin-kexin type 9 levels with resistin in lean and obese subjects. Clin Biochem. 2012;45:1522-1524
Huijgen R, Boekholdt SM, Arsenault BJ, Bao W, Davaine JM, Tabet F, Petrides F, Rye KA, DeMicco DA, Barter PJ, Kastelein JJ, Lambert G. Plasma pcsk9 levels and clinical outcomes in the tnt (treating to new targets) trial: A nested case-control study. J Am Coll Cardiol. 2012;59:1778-1784
Heymann MF, Herisson F, Davaine JM, Charrier C, Battaglia S, Passuti N, Lambert G, Goueffic Y, Heymann D. Role of the opg/rank/rankl triad in calcifications of the atheromatous plaques: Comparison between carotid and femoral beds. Cytokine. 2012;58:300-306
Golipour A, David L, Liu Y, Jayakumaran G, Hirsch CL, Trcka D, Wrana JL. A late transition in somatic cell reprogramming requires regulators distinct from the pluripotency network. Cell Stem Cell. 2012;11:769-782
Farokhi F, Wielgosz-Collin G, Robic A, Debitus C, Malleter M, Roussakis C, Kornprobst JM, Barnathan G. Antiproliferative activity against human non-small cell lung cancer of two o-alkyl-diglycosylglycerols from the marine sponges myrmekioderma dendyi and trikentrion laeve. Eur J Med Chem. 2012;49:406-410
Constantinides A, Kappelle PJ, Lambert G, Dullaart RP. Plasma lipoprotein-associated phospholipase a2 is inversely correlated with proprotein convertase subtilisin-kexin type 9. Arch Med Res. 2012;43:11-14
Cario-Toumaniantz C, Ferland-McCollough D, Chadeuf G, Toumaniantz G, Rodriguez M, Galizzi JP, Lockhart B, Bril A, Scalbert E, Loirand G, Pacaud P. Rhoa guanine exchange factor expression profile in arteries: Evidence for a rho kinase-dependent negative feedback in angiotensin ii-dependent hypertension. Am J Physiol Cell Physiol. 2012;302:C1394-1404
Bidart M, Ricard N, Levet S, Samson M, Mallet C, David L, Subileau M, Tillet E, Feige JJ, Bailly S. Bmp9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain. Cell Mol Life Sci. 2012;69:313-324

2011

Wood P, Mulay V, Darabi M, Chan KC, Heeren J, Pol A, Lambert G, Rye KA, Enrich C, Grewal T. Ras/mitogen-activated protein kinase (mapk) signaling modulates protein stability and cell surface expression of scavenger receptor sr-bi. J Biol Chem. 2011;286:23077-23092
Tabet F, Lambert G, Cuesta Torres LF, Hou L, Sotirchos I, Touyz RM, Jenkins AJ, Barter PJ, Rye KA. Lipid-free apolipoprotein a-i and discoidal reconstituted high-density lipoproteins differentially inhibit glucose-induced oxidative stress in human macrophages. Arterioscler Thromb Vasc Biol. 2011;31:1192-1200
Roncalli J, Mouquet F, Piot C, Trochu JN, Le Corvoisier P, Neuder Y, Le Tourneau T, Agostini D, Gaxotte V, Sportouch C, Galinier M, Crochet D, Teiger E, Richard MJ, Polge AS, Beregi JP, Manrique A, Carrie D, Susen S, Klein B, Parini A, Lamirault G, Croisille P, Rouard H, Bourin P, Nguyen JM, Delasalle B, Vanzetto G, Van Belle E, Lemarchand P. Intracoronary autologous mononucleated bone marrow cell infusion for acute myocardial infarction: Results of the randomized multicenter bonami trial. Eur Heart J. 2011;32:1748-1757
Roncalli J, Lemarchand P. Autologous bone marrow cells and ischemic cardiomyopathy. Future Cardiol. 2011;7:603-607
Merline R, Moreth K, Beckmann J, Nastase MV, Zeng-Brouwers J, Tralhao JG, Lemarchand P, Pfeilschifter J, Schaefer RM, Iozzo RV, Schaefer L. Signaling by the matrix proteoglycan decorin controls inflammation and cancer through pdcd4 and microrna-21. Sci Signal. 2011;4:ra75
Lemarchand P. [cell therapy in acute myocardial infarction]. Rev Med Interne. 2011;32 Suppl 2:S208-209
Kappelle PJ, Lambert G, Dullaart RP. Plasma proprotein convertase subtilisin-kexin type 9 does not change during 24h insulin infusion in healthy subjects and type 2 diabetic patients. Atherosclerosis. 2011;214:432-435
Kappelle PJ, Lambert G, Dahlback B, Nielsen LB, Dullaart RP. Relationship of plasma apolipoprotein m with proprotein convertase subtilisin-kexin type 9 levels in non-diabetic subjects. Atherosclerosis. 2011;214:492-494
Huang T, David L, Mendoza V, Yang Y, Villarreal M, De K, Sun L, Fang X, Lopez-Casillas F, Wrana JL, Hinck AP. Tgf-beta signalling is mediated by two autonomously functioning tbetari:Tbetarii pairs. EMBO J. 2011;30:1263-1276
Herisson F, Heymann MF, Chetiveaux M, Charrier C, Battaglia S, Pilet P, Rouillon T, Krempf M, Lemarchand P, Heymann D, Goueffic Y. Carotid and femoral atherosclerotic plaques show different morphology. Atherosclerosis. 2011;216:348-354
Akram ON, Bursill C, Desai R, Heather AK, Kazlauskas R, Handelsman DJ, Lambert G. Evaluation of androgenic activity of nutraceutical-derived steroids using mammalian and yeast in vitro androgen bioassays. Anal Chem. 2011;83:2065-2074

2010

Toumaniantz G, Ferland-McCollough D, Cario-Toumaniantz C, Pacaud P, Loirand G. The rho protein exchange factor vav3 regulates vascular smooth muscle cell proliferation and migration. Cardiovasc Res. 2010;86:131-140
Tabet F, Remaley AT, Segaliny AI, Millet J, Yan L, Nakhla S, Barter PJ, Rye KA, Lambert G. The 5a apolipoprotein a-i mimetic peptide displays antiinflammatory and antioxidant properties in vivo and in vitro. Arterioscler Thromb Vasc Biol. 2010;30:246-252
Samavarchi-Tehrani P, Golipour A, David L, Sung HK, Beyer TA, Datti A, Woltjen K, Nagy A, Wrana JL. Functional genomics reveals a bmp-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell. 2010;7:64-77
Rolli-Derkinderen M, Toumaniantz G, Pacaud P, Loirand G. Rhoa phosphorylation induces rac1 release from guanine dissociation inhibitor alpha and stimulation of vascular smooth muscle cell migration. Mol Cell Biol. 2010;30:4786-4796
Nobecourt E, Tabet F, Lambert G, Puranik R, Bao S, Yan L, Davies MJ, Brown BE, Jenkins AJ, Dusting GJ, Bonnet DJ, Curtiss LK, Barter PJ, Rye KA. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein a-i. Arterioscler Thromb Vasc Biol. 2010;30:766-772
Malleter M, Jacquot C, Moreau D, Tomasoni C, Tsvetanova M, Chinou I, Juge M, Pineau A, Le Pape P, Roussakis C. A novel large regulator rna, b2, partially overlaps the hef1/nedd9/cas-l gene. Int J Mol Med. 2010;25:897-903
Lamirault G, Meur NL, Roussel JC, Cunff MF, Baron D, Bihouee A, Guisle I, Raharijaona M, Ramstein G, Teusan R, Chevalier C, Gueffet JP, Trochu JN, Leger JJ, Houlgatte R, Steenman M. Molecular risk stratification in advanced heart failure patients. J Cell Mol Med. 2010;14:1443-1452
Kanashiro-Takeuchi RM, Tziomalos K, Takeuchi LM, Treuer AV, Lamirault G, Dulce R, Hurtado M, Song Y, Block NL, Rick F, Klukovits A, Hu Q, Varga JL, Schally AV, Hare JM. Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction. Proc Natl Acad Sci U S A. 2010;107:2604-2609
Heidecker B, Lamirault G, Kasper EK, Wittstein IS, Champion HC, Breton E, Russell SD, Hall J, Kittleson MM, Baughman KL, Hare JM. The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences. Eur Heart J. 2010;31:1188-1196
Guilluy C, Bregeon J, Toumaniantz G, Rolli-Derkinderen M, Retailleau K, Loufrani L, Henrion D, Scalbert E, Bril A, Torres RM, Offermanns S, Pacaud P, Loirand G. The rho exchange factor arhgef1 mediates the effects of angiotensin ii on vascular tone and blood pressure. Nat Med. 2010;16:183-190
Forest VF, Tirouvanziam AM, Perigaud C, Fernandes S, Fusellier MS, Desfontis JC, Toquet CS, Heymann MF, Crochet DP, Lemarchand PF. Cell distribution after intracoronary bone marrow stem cell delivery in damaged and undamaged myocardium: Implications for clinical trials. Stem Cell Res Ther. 2010;1:4
David L. [mesenchymal-to-epithelial transition: A necessary initial step towards reprogrammation of fibroblasts]. Med Sci (Paris). 2010;26:1030-1032
Brossard D, El Kihel L, Clement M, Sebbahi W, Khalid M, Roussakis C, Rault S. Synthesis of bile acid derivatives and in vitro cytotoxic activity with pro-apoptotic process on multiple myeloma (kms-11), glioblastoma multiforme (gbm), and colonic carcinoma (hct-116) human cell lines. Eur J Med Chem. 2010;45:2912-2918
Akram ON, Bernier A, Petrides F, Wong G, Lambert G. Beyond ldl cholesterol, a new role for pcsk9. Arterioscler Thromb Vasc Biol. 2010;30:1279-1281

2009

Viloria-Petit AM, David L, Jia JY, Erdemir T, Bane AL, Pinnaduwage D, Roncari L, Narimatsu M, Bose R, Moffat J, Wong JW, Kerbel RS, O’Malley FP, Andrulis IL, Wrana JL. A role for the tgfbeta-par6 polarity pathway in breast cancer progression. Proc Natl Acad Sci U S A. 2009;106:14028-14033
Rye KA, Bursill CA, Lambert G, Tabet F, Barter PJ. The metabolism and anti-atherogenic properties of hdl. J Lipid Res. 2009;50 Suppl:S195-200
Patel S, Puranik R, Nakhla S, Lundman P, Stocker R, Wang XS, Lambert G, Rye KA, Barter PJ, Nicholls SJ, Celermajer DS. Acute hypertriglyceridaemia in humans increases the triglyceride content and decreases the anti-inflammatory capacity of high density lipoproteins. Atherosclerosis. 2009;204:424-428
Lemarchand P. [cell therapy for acute myocardial infarction]. Transfus Clin Biol. 2009;16:146-147
Leblond AL, Naud P, Forest V, Gourden C, Sagan C, Romefort B, Mathieu E, Delorme B, Collin C, Pages JC, Sensebe L, Pitard B, Lemarchand P. Developing cell therapy techniques for respiratory disease: Intratracheal delivery of genetically engineered stem cells in a murine model of airway injury. Hum Gene Ther. 2009;20:1329-1343
Lambert G, Charlton F, Rye KA, Piper DE. Molecular basis of pcsk9 function. Atherosclerosis. 2009;203:1-7
Kanashiro-Takeuchi RM, Heidecker B, Lamirault G, Dharamsi JW, Hare JM. Sex-specific impact of aldosterone receptor antagonism on ventricular remodeling and gene expression after myocardial infarction. Clin Transl Sci. 2009;2:134-142
Gaborit N, Wichter T, Varro A, Szuts V, Lamirault G, Eckardt L, Paul M, Breithardt G, Schulze-Bahr E, Escande D, Nattel S, Demolombe S. Transcriptional profiling of ion channel genes in brugada syndrome and other right ventricular arrhythmogenic diseases. Eur Heart J. 2009;30:487-496
Fernandes S, van Rijen HV, Forest V, Evain S, Leblond AL, Merot J, Charpentier F, de Bakker JM, Lemarchand P. Cardiac cell therapy: Overexpression of connexin43 in skeletal myoblasts and prevention of ventricular arrhythmias. J Cell Mol Med. 2009;13:3703-3712
David L, Feige JJ, Bailly S. Emerging role of bone morphogenetic proteins in angiogenesis. Cytokine Growth Factor Rev. 2009;20:203-212
Chopard A, Lecunff M, Danger R, Lamirault G, Bihouee A, Teusan R, Jasmin BJ, Marini JF, Leger JJ. Large-scale mrna analysis of female skeletal muscles during 60 days of bed rest with and without exercise or dietary protein supplementation as countermeasures. Physiol Genomics. 2009;38:291-302
Chan DC, Lambert G, Barrett PH, Rye KA, Ooi EM, Watts GF. Plasma proprotein convertase subtilisin/kexin type 9: A marker of ldl apolipoprotein b-100 catabolism? Clin Chem. 2009;55:2049-2052
Beigi F, Oskouei BN, Zheng M, Cooke CA, Lamirault G, Hare JM. Cardiac nitric oxide synthase-1 localization within the cardiomyocyte is accompanied by the adaptor protein, capon. Nitric Oxide. 2009;21:226-233
Audigane L, Kerfant BG, El Harchi A, Lorenzen-Schmidt I, Toumaniantz G, Cantereau A, Potreau D, Charpentier F, Noireaud J, Gauthier C. Rabbit, a relevant model for the study of cardiac beta 3-adrenoceptors. Exp Physiol. 2009;94:400-411

2008

Roussel JC, Baron O, Perigaud C, Bizouarn P, Pattier S, Habash O, Mugniot A, Petit T, Michaud JL, Heymann MF, Treilhaud M, Trochu JN, Gueffet JP, Lamirault G, Duveau D, Despins P. Outcome of heart transplants 15 to 20 years ago: Graft survival, post-transplant morbidity, and risk factors for mortality. J Heart Lung Transplant. 2008;27:486-493
Moreau D, Jacquot C, Tsita P, Chinou I, Tomasoni C, Juge M, Antoniadou-Vyza E, Martignat L, Pineau A, Roussakis C. Original triazine inductor of new specific molecular targets, with antitumor activity against nonsmall cell lung cancer. Int J Cancer. 2008;123:2676-2683
Lambert G, Ancellin N, Charlton F, Comas D, Pilot J, Keech A, Patel S, Sullivan DR, Cohn JS, Rye KA, Barter PJ. Plasma pcsk9 concentrations correlate with ldl and total cholesterol in diabetic patients and are decreased by fenofibrate treatment. Clin Chem. 2008;54:1038-1045
Homer VM, Marais AD, Charlton F, Laurie AD, Hurndell N, Scott R, Mangili F, Sullivan DR, Barter PJ, Rye KA, George PM, Lambert G. Identification and characterization of two non-secreted pcsk9 mutants associated with familial hypercholesterolemia in cohorts from new zealand and south africa. Atherosclerosis. 2008;196:659-666
David L, Mallet C, Keramidas M, Lamande N, Gasc JM, Dupuis-Girod S, Plauchu H, Feige JJ, Bailly S. Bone morphogenetic protein-9 is a circulating vascular quiescence factor. Circ Res. 2008;102:914-922
Ahn SH, Shah YM, Inoue J, Morimura K, Kim I, Yim S, Lambert G, Kurotani R, Nagashima K, Gonzalez FJ, Inoue Y. Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease. Inflamm Bowel Dis. 2008;14:908-920